It says on the bottle I can’t take an antacid for at least four hours after taking the Plaquenil. I hate heart burn:( I take a PPI (proton pump inhibitor) essentially antacid in the morning that is supposed to last all day. I would ask your pharmacist first and see if it matters whether it is just a 'tums' or medication strength. I think if it keeps happening I’ll go talk to my pharmacist to see what they recommend. Has anyone else experienced heartburn while taking Plaquenil and if so what did you do to avoid or ease the heartburn? If they are not able to give you an answer your Family Dr or Rheumatoid will know. Fortunately the heartburn goes away after a few hours, but those few hours are very uncomfortable! Plaquenil and eye floaters Which hydroxychloroquine manufacturer not work Plaquenil and cold medicine Plaquenil hydroxychloroquine is a medication most known for its original purpose of treating or preventing malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Hi Enjoy, You are right that only antacids react with plaquenil, not acid reducers, at least for the main ones that I checked on On which is one of our approved sites for linking in the forum, you can look up all your medications and the drug interaction listings are especially nice. Some antacids can make it harder for your body to absorb hydroxychloroquine. Hydroxychloroquine can cause serious liver or heart problems, especially if you use certain medicines at the same time. But that's just the optimum way to take it, not the necessity. Sometimes what is suggested (no antacid for 4 hours) is not necessarily required if it means you can't or don't want to take your plaquenil anymore. the antacid will affect the absorption of the plaquenil and the amount your body can absorb. Hydroxychloroquine and antacids Hydroxychloroquine Side-effects, uses, time to work, Hydroxychloroquin and acid reducers - Sclero Forums MAIN. Chloroquine proguanil side effectsCan hydroxychloroquine cause dry eyes Also, generic plaquenil hydroxychloroquine is often associated with more GI side effets than the name brand. Arthritis Center Founded in 1998, the Arthritis Center at Johns Hopkins is dedicated to providing quality education to patients and healthcare providers alike. Stomach problems with Plaquenil • Johns Hopkins Arthritis Center. Hydroxychloroquine - Side Effects, Dosage, Interactions.. Plaquenil Uses, Dosage & Side Effects -. Antacids Major Hydroxychloroquine absorption may be reduced by antacids as has been observed with the structurally similar chloroquine. Administer hydroxychloroquine and antacids at least 4 hours apart. Section of the Plaquenil hydroxychloroquine drug label regarding cardiac effects, including cardiomyopathy and QT prolongation, and hypoglycemia. and for the prophylaxis of malaria in geographic areas where chloroquine resistance is not reported. Hydroxychloroquine also known by its popular brand name Plaquenil is an oral medication that is commonly used to treat a variety of autoimmune diseases including systemic lupus, dermatomyositis, rheumatoid arthritis, Sjogren’s and many other conditions as well. In the field of hair loss, conditions such as lichen planopilaris, frontal fibrosing alopecia and discoid lupus are frequently treated with hydroxychloroquine.