Controlled studies in pregnant women show no evidence of fetal risk. Either animal studies show no risk but human studies not available or animal studies showed minor risks and human studies done and showed no risk. Animal studies show risk and human studies not available or neither animal nor human studies done. Contact the applicable plan provider for the most current information. D: Use in LIFE-THREATENING emergencies when no safer drug available. Macular oct plaquenil toxicity Plaquenil and atenolol Chloroquine tablets lloyds Chloroquine sensitive p falciparum area Feb 17, 2015 In most cases, 250 mg tablets have an equivalence of 150 mg chloroquine base, and 500 mg tablets have an equivalence of 300 mg chloroquine base. Although the purity mentioned above is generally accurate, it would be best to verify the chloroquine base contained in the tablets of your choice in order to be able to properly calculate the exact dosage. Suppression 5 mg/kg calculated as base orally on exactly the same day each week; the dose should not exceed 400 mg regardless of weight Comments-Suppressive therapy should begin 2 weeks prior to exposure; however, failing this, an initial dose of 10 mg/kg calculated as base may be taken in 2 divided doses 6 hours apart. The dose is usually 5 milligram mg per kilogram kg of body weight once per week on the same day each week starting 2 weeks before traveling to an area where malaria occurs, and continued for 8 weeks after leaving the area. For treatment of malaria Adults—At first, 1000 milligrams mg once a day. Active against erythrocytic forms of Plasmodium vivax & P. malariae and most strains of Plasmodium falciparum Precise mechanism not known Bioavailability: ~89% Peak plasma time: 1-2 hr Distributed widely in body tissues (eg, eyes, heart, kidneys, liver, lungs) where retention prolonged; crosses placenta; enters breast milk Partially in liver Half-life: 3-5 days Excretion: urine (~70% as unchanged drug); acidification of urine increases elimination Small amounts may be present in urine months following discontinuation of therapy The above information is provided for general informational and educational purposes only. Chloroquine dose per kg More Medicines Used for Malaria - Hesperian Health Guides, Hydroxychloroquine Dosage Guide with Precautions - How dispose of chloroquine safelyVitamin c and plaquenil Oct 01, 2018 This represents a total dose of 2.5 g Chloroquine phosphate or 1.5 g base in three days. Infants and Children In infants and children, the recommended dose is 10 mg base/kg followed by 5 mg based/kg at 6, 24 and 36 hours total dose 25 mg based/kg. The pediatric dose should never exceed the adult dose regardless of weight. Chloroquine - FDA prescribing information, side effects and uses. Chloroquine Oral Route Proper Use - Mayo Clinic. Post-exposure Chloroquine Prophylaxis COVID19. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 milligram mg per kilogram kg of body weight once per week on the same day each week starting 2 weeks before traveling to an area where malaria occurs, and continued for 8 weeks after leaving the area. For treatment of malaria Adults—At first, 1000 milligrams mg once a day. Then, 500 mg 6 to 8 hours after the first dose, and 500 mg on the second and third days of treatment. Adults with low body weight and children—Dose is based on body weight and must be determined by your doctor. At first, 10 milligram mg per kilogram kg of body weight. The Weight Based Dose Calculator is used for weight based dosing. The parameters for the calculator include dosage, weight, med amount, per volume.