It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Hydroxychloroquine do not crush Human anti-chimeric antibody rituximab hydroxychloroquine Hydroxychloroquine sulfate drug classification Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Plaquenil and Irritable bowel syndrome - from FDA reports Summary Irritable bowel syndrome is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 6 - 12 months, also take medication Enbrel, and have Pain. I am afraid to stop plaquenil because my initial flare was so unbelievably painful. Since taking plaquenil I have been serious flare free. I developed digestive issues a couple of years ago and decided to eliminate gluten even though I did not test for celiac. My bowel problem has improved to the point that I can rejoin normal people. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil bowel problems Plaquenil eye problems Mayo Clinic Connect, Will you have Irritable bowel syndrome with Plaquenil. Benefits of plaquenil for lupusLowest prices for hydroxychloroquineRheumatology.org plaquenil On Plaquenil for 18 months; spasms/pain, other factors persisted. Developed acute candidas/hospitalized for femoral hernia repair and small bowel obstruction. Took myself off Plaquenil one month ago, and I'm feeling 100% better. August 31, 2016 at AM Reasonably Well Plaquenil FAQ. Plaquenil/Hydroxychloroquine and stomach problems?. Hydroxychloroquine for Crohns Disease and Ulcerative.. I pretty much solved the problem by taking the Plaquenil with full meals and by adding a Probiotic. I think the Probiotic helped the most. After I started the Probiotic, the loose stools pretty much stopped, although I do seem to have more stools than I used to have before starting Plaquenil. Nov 28, 2010 Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells these are messengers for your immune system, if you will from interacting with your T-Cells a special type of white blood cell which through a convoluted and boring process, causes inflammation when an infection is found, and these basically malfunction with inflammatory disorders. Tell your doctor if any of the following side effects, as they may be indications of a more serious reaction Headache. Loss of appetite. Dizziness. Nausea. Diarrhea, vomiting, or stomach pain. Skin rash.