Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Remission with plaquenil Weiggt gain tryibg to get off plaquenil Plaquenil derived from Nov 16, 2004 For people with rheumatoid arthritis, methotrexate is the treatment of choice in reducing pain and inflammation. But there's evidence the drug can activate a virus that can increase the risk of. This study evaluates the efficacy of the combination of methotrexate and hydroxychloroquine against leflunomide, a new DMARD as initial therapy in severe active rheumatoid arthritis. Hydroxychloroquine is known to increase the potency of methotrexate as well as increase its safety profile and reduce the dose. Nov 13, 2012 If patients did not go into remission after four months, they were randomized either to a combination of multiple DMARDS and low-dose prednisone arm 1 or to adalimumab ADA and methotrexate arm 2. Arm 1 involved 25 mg/wk MTX, 400 mg/day hydroxychloroquine, 2000mg/day sulphasalazine, and 7.5 mg/day of prednisone. Recently my eyes have felt sore and, after posting a question on this site, I am seeing my GP on Monday. Thanks Hi Catjones I have been taking this combination, started on both of them in January this year. Combination of plaquenil and methotrexate Compare Plaquenil vs Methotrexate -, Evaluation of efficacy of combination of methotrexate and. Chloroquine hydrochloride dosagePlaquenil tendon pain If patients did not go into remission after four months, they were randomized either to a combination of multiple DMARDS and low-dose prednisone arm 1 or to adalimumab ADA and methotrexate arm 2. Arm 1 involved 25 mg/wk MTX, 400 mg/day hydroxychloroquine, 2000mg/day sulphasalazine, and 7.5 mg/day of prednisone. Study Shows Methotrexate and Prednisone Combination.. Study Shows Methotrexate and Prednisone Combination Therapy.. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Learn about drug interactions between hydroxychloroquine oral and methotrexate sodium oral and use the RxList drug interaction checker to check drug combinations. The efficacy of hydroxychloroquine as a step-down therapy from methotrexate- hydroxychloroquine combination therapy has also been investigated; after 24 weeks of open treatment, 121 patients who responded to methotrexate- hydroxychloroquine combination therapy 7.5-15 mg/week and 400 mg/day, respectively were randomly assigned to receive. With Plaquenil, the possibility of permanent vision damage scares me. I also want to be sure that I'm taking a drug that will slow/stop the progression of the disease. I've read elsewhere that Plaquenil is not as strong/effective in the treatment of early RA. With Methotrexate, the reports of nausea and possible liver damage are concerning.