It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Nursing interventions for hydroxychloroquine Plaquenil prsivribed by rheumatilogshrs cut in half Hydroxychloroquine ocular side effects Hydroxychloroquine is a one of a number of drugs which have been used for many years in the treatment of malaria. Fortunately, it was discovered these drugs often are helpful in the treatment of various rheumatic diseases, particularly systemic lupus erythematosus SLE or "Lupus" and rheumatoid arthritis. Hydroxychloroquine Plaquenil Chloroquine Aralen Quinacrine Atabrine What are anti-malarial drugs, and why are they used to treat lupus? Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. Systemic lupus erythematosus is a disease that continues to evolve over time. Thus, a patient who presents with skin and joint disease remains at risk for renal disease even after having lupus. For prolonged treatment of lupus or arthritis, adverse effects include the acute symptoms, plus altered eye pigmentation, acne, anaemia, bleaching of hair, blisters in mouth and eyes, blood disorders, convulsions, vision difficulties, diminished reflexes, emotional changes, excessive coloring of the skin, hearing loss, hives, itching, liver problems or liver failure, loss of hair, muscle paralysis, weakness or atrophy, nightmares, psoriasis, reading difficulties, tinnitus, skin inflammation and scaling, skin rash, vertigo, weight loss, and occasionally urinary incontinence. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. For short-term treatment of acute malaria, adverse effects can include abdominal cramps, diarrhea, heart problems, reduced appetite, headache, nausea and vomiting. Chloroquine sle Aralen chloroquine Malaria Drug Side Effects & Dosage, Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus. Plaquenil method of actionCan plaquenil cause anxiety Find patient medical information for Chloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. Chloroquine Oral Uses, Side Effects, Interactions.. Treatment of Systemic Lupus Erythematosus An Update.. Hydroxychloroquine Plaquenil Side Effects & Dosage for Malaria. Chloroquine is a medication first developed as an anti-malarial that has been used for many years to help treat lupus systemic lupus erythematosus, or SLE and rheumatoid arthritis. If a patient responds to treatment with an anti-malarial, in general it will continue to be used indefinitely. Chloroquine is a medication used to prevent and to treat malaria in areas where malaria is known to be sensitive to its effects. Certain types of malaria, resistant strains, and complicated cases typically require different or additional medication. Chloroquine is only found in individuals that have used or taken this drug. It is a prototypical antimalarial agent with a mechanism that is not well understood. It has also been used to treat rheumatoid arthritis, systemic lupus erythematosus, and in the systemic therapy of amebic liver abscesses.