Systemic lupus erythematosus (SLE) is an autoimmune disease that may affect nearly any organ system in the human body. When this disease affects the kidney, it is termed . Plaquenil antiviral how does it work Hydroxychloroquine and liver Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Lupus nephritis is a frequent complication in people who have systemic lupus erythematosus — more commonly known as lupus. Lupus is an autoimmune disease. It causes your immune system to produce proteins called autoantibodies that attack your own tissues and organs, including the kidneys. The antimalarials most often prescribed to people with lupus are Hydroxychloroquine Plaquenil® Chloroquine Aralen® Quinacrine Atabrine® 2-3; Hydroxychloroquine is prescribed the most often because it is thought to have the fewest side effects. Chloroquine and quinacrine are prescribed when hydroxychloroquine cannot be used. Even with the many recent advances in treatments for lupus nephritis, 10% to 15% of treated patients will still progress to end-stage renal disease (ESRD) and require dialysis or transplant. The condition is often associated with poorer outcomes and is of particular interest for this reason. Chloroquine lupus nephritis Lupus nephritis - Diagnosis and treatment - Mayo Clinic, Lupus nephritis Disease Reference Guide - Quarantine procedure for saltwater fish chloroquinePlaquenil color vision effectsPlaquenil and prednisone side effectsPlaquenil and liver enzymes Lupus nephritis is a type of kidney disease caused by systemic lupus erythematosus SLE or lupus. Lupus is an autoimmune disease —a disorder in which the body’s immune system attacks the body’s own cells and organs. Lupus and Kidney Disease Lupus Nephritis NIDDK. Antimalarials. Hydroxychloroquine A multifaceted treatment in lupus - EM.. Lupus nephritis is kidney disease that is caused by lupus. To start, it must be understood that there are many forms of kidney disease that are referred to as lupus nephritis. Each form is distinguished by characteristic patterns of abnormalities as defined by a kidney biopsy. Hydroxychloroquine HCQ is a recommended drug in systemic lupus erythematosus SLE. It has a long terminal half-life, making it an attractive target for therapeutic drug monitoring. The aim of this study was to establish a relationship between blood HCQ concentration and lupus nephritis activity. Jun 15, 2009 Lupus nephritis patients n=256 from LUMINA n=635, a multiethnic cohort of African Americans, Hispanics and Caucasians, age ≥16 years, disease duration ≤5 years at baseline T0 were studied.