Friends and family help but they really just dont get it! Anyways- been diagnosed and have been taking plaquenil since around October- it was helping but my wrists and fingers were still in so much pain that I couldn't even get dressed in the mornings! So I was taking dose packs to help w the pain and my rheumatology finally put me on prednisone- TERRIBLE. I couldnt sleep at night, had awful night sweats, weight gain...it. Should i take plaquenil in the morning or night Chagas disease is treated with chloroquine t f Rheumatoid arthritis is a chronic disorder for which there is no known cure. Fortunately in the last few years, a shift in strategy toward the earlier institution of disease modifying drugs and the availability of new classes of medications have greatly improved the outcomes that can be expected by most patients. For patients with a disease duration less than 6 months, clinical practice guidelines recommend use of combination DMARDs such as sulfasalazine plus hydroxychloroquine for those with moderate disease activity and poor prognostic features and is an option for those with high disease activity and poor prognostic features. Does Plaquenil Interact with other Medications? Severe Interactions. These medications are not usually taken together. Consult your healthcare professional e.g. doctor or pharmacist for more in. So my doctor wanted to put me on methotrexate and I read sooo many terrible things about it that I begged her to let me try something else first before going to the extreme w the methotrexate. Being a 23 yr old female who is getting married in July- weight gain feels like the worst thing that could happen to you. Plaquenil and sulfasalazine combination Treatment of Rheumatoid Arthritis with Methotrexate Alone., Plaquenil hydroxychloroquine sulfate dose, indications. Plaquenil peakHydroxychloroquine 200 mg good rxCan plaquenil cause pancreatitisChloroquine cytotoxicHydroxychloroquine during pregnancy Background/Purpose The combination of methotrexate MTX, sulfasalazine SSZ and hydroxychloroquine HCQ triple therapy is a highly effective and well-tolerated treatment in rheumatoid arthritis RA. While MTX is the cornerstone of most successful combination therapies, not all patients are candidates for, or tolerate, MTX. Leflunomide, Sulfasalazine and Hydroxychloroquine for.. Plaquenil Oral Interactions with Other Medication. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. The curcumin groups, especially the combination group, showed significant improvement in comparison to the diclofenac only group. Also, curcumin was found to be safe and did not cause side effects. Research suggests that it is safe to take turmeric when taking arthritis medications. If the plaquenil is helping and they say you need it, I'd take it - the side effects will go away. I've not had experience with sulfasalazine - but from what I've read, the side effects of that med are about the same as those of plaquenil. BTW - sulfasalazine is an anti-inflammatory. Waddie I have to go on sulfa and plaquenil with my MTX. Is it helping any of you? Enbrel isn't working for me because of infections. My dx wanted to try Humira but I didn't want to continue on biologics, I just want a break. Aleva.combination of mtx, plaquenil and sulfasalazine has helped me quite a bit over the yrs. It certainly is worth.