I've been on plaquenil for 6 months for suspected Sjogren's syndrome (I don't have antibodies for Sjorgren's or Lupus but I do have Hashimoto's and have all the symptoms for Sjorgren's so the rheumatologist suggested a trial of plaquenil). Basically I've been on the drug since January and saw the rheumatologist on Wednesday to see how things are going. Plaquenil dosage for discoid lupus Chloroquine resistant malaria drug of choice What is chloroquine base Aug 27, 2010 i was just curious if i was to try plaquenil again for a few days/weeks if you decide to stop do you have to wean off like a lot of drugs or can you simply stop taking it.thanks. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA, and is updated regularly. On eHealthMe, you can evaluate side effects and drug interactions from 16 million FDA reports. The results are personalized to your gender and age 0-99+. Hi Mandie, I had these issues both on & off Plaquenil. I believe it was caused by the lupus rather than the meds. But you should NOT throw all your meds away, this type of reaction could be an extension of the psychological issues you are having. If your lupus gets worse because you have stopped your meds, these issues will too. Get help asap. I do think it's helped with fatigue and muscle pain but it's hard for me to compare to Xmas as when the improvement is so gradual I think it's really hard to notice on a gradual basis. I *think* I'm improving but it's been a gradual process and I said to him that it's quite hard to tell how much of an improvement I'm feeling. Do you have to be weaned off of plaquenil Taking Plaquenil for Rheumatoid Arthritis, Will you have Withdrawal syndrome with Plaquenil - eHealthMe Taking hydroxychloroquinePlaquenil nausea redditKinds o generic hydroxychloroquineHydroxychloroquine cause urinary infectionsPlaquenil freshness disposal You see, when you introduce prednisone which the body recognizes as cortisol to the body, the adrenals stop making their own supply. The theory behind tapering off of steroids like prednisone is that by slowly removing the external steroid source, the body can adapt and begin making its own again with less stress placed on the system. Prednisone Tapering Schedule - Doctor Scott Health Blog. Does Plaquenil affect your temperament? - LUPUS UK. Hydroxychloroquine plaquenil withdrawl? - LUPUS UK. Hi everybody! I recently went to the doc and he recommended that I try cutting my Plaquenil in half from 400mg to 200mg/day. I have been on it since March, 2002. It's been about a week and I have noticed a few slight changes, mainly a little stiffness in my fingers and feeling a little fatigued. If your rheumatoid arthritis symptoms do not improve, or if they worsen, stop taking the drug and call your doctor. Once you and your doctor are sure the drug works for you, do not stop taking hydroxychloroquine without talking to your doctor. Symptoms of rheumatoid arthritis will return if you stop taking hydroxychloroquine. I was just curious if i was to try plaquenil again for a few days/weeks if you decide to stop do you have to wean off like a lot of drugs or can you simply stop taking it.thanks.