In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Hydroxychloroquine blood test Mycophenolate and hydroxychloroquine Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Macular Society Eye screening for patients taking hydroxychloroquine Hydroxychloroquine is a medication used to treat several conditions including rheumatoid arthritis, systemic lupus erythematosus, some skin conditions especially photosensitive ones and others that involve inflammation. It was previously used in the treatment and Sep 13, 2019 red irritated eyes; red skin lesions, often with a purple center; severe mood or mental changes; sore throat sores, ulcers, or white spots on the lips or in the mouth; sticking out of the tongue; stomach pain; swelling of the feet or lower legs; swollen or painful glands; trouble with breathing, speaking, or swallowing As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Plaquenil and swelling eyes Plaquenil Side Effects on Your Eyes and Vision, Eye screening for patients taking hydroxychloroquine Plaquenil The drug plaquenil Red irritated eyes red skin lesions, often with a purple center severe mood or mental changes sore throat sores, ulcers, or white spots on the lips or in the mouth sticking out of the tongue stomach pain swelling of the feet or lower legs swollen or painful glands trouble with breathing, speaking, or swallowing Hydroxychloroquine Oral Route Side Effects - Mayo Clinic. Plaquenil Side Effects Common, Severe, Long Term -. Hydroxychloroquine toxicity - EyeWiki. Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs. Plaquenil is the brand name of hydroxychloroquine, a drug used to prevent or treat malaria 2. Plaquenil is also used for long-term treatment of autoimmune diseases such as rheumatoid arthritis RA and systemic lupus erythmatosis. According to the Mayo Clinic, it can take up to six months' constant use before an effect is seen in RA 1. Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. Apr 10, 2019 Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking Plaquenil and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes.