Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Hydroxychloroquine success stories How long does plaquenil take to kick in Macrobid and plaquenil Plaquenil insert Before using Plaquenil, tell your doctor if you are allergic to any drugs, or if you have psoriasis, porphyria, liver disease, alcoholism, or glucose-6-phosphate dehydrogenase G-6-PD deficiency. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. Note This document contains side effect information about hydroxychloroquine. Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Antimalarials Plaquenil, Quinacrine, chloroquine and hydroxychloroquine may cause a flare of psoriasis, usually two to three weeks after the drug is taken. Hydroxychloroquine is the least likely to cause side effects. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Can plaquenil cause psoriasis Psoriasis vs. Lupus What’s the Difference?, Plaquenil Side Effects Common, Severe, Long Term - Can you take tylenol with plaquenilPlaquenil induced cardiomyopathy People can avoid many of the triggers for psoriasis. The first step is to find out what causes flares, and then take steps to reduce them. The specific triggers differ from people-to-person. Psoriasis 11 triggers and how to avoid them. Psoriasis Causes & Triggers National Psoriasis Foundation. Long-Term Side Effects of Plaquenil for Rheumatoid.. This is a case where Plaquenil likely triggered new-onset psoriasis in a patient who was genetically susceptible. There are several other drugs that would likely be beneficial for both diseases by virtue of their anti-inflammatory or immunosuppressive effects, namely, acitretin Soriatane. Find information about common, infrequent and rare side effects of Plaquenil Oral. If your plans include travel to southern Africa or another part of the world where malaria is common, you might need medicine to protect yourself against the mosquito-borne disease. But be aware. If you have psoriasis, chloroquine Aralen and hydroxychloroquine Plaquenil can cause problems.