Her rheumatologist instructed her to undergo a baseline ocular examination prior to initiating Plaquenil (hydroxychloroquine, Sanofi-Aventis) therapy. Toxic maculopathy associated with chloroquine use was first documented in the literature five decades ago.1 In the United States, Plaquenil––an analog to chloroquine––is used to treat a variety of conditions, including rheumatoid arthritis, lupus and several distinct inflammatory disorders. Although the incidence of macular toxicity is infrequent with Plaquenil use (at a dosage of 200mg or 400mg q.d.), its visual impact can be devastating. Brazil nuts and plaquenil Plaquenil and back pain Can hydroxy chloroquine affect birth control Aug 29, 2014 As a precaution, patients treated with Plaquenil are advised to get a baseline eye exam prior to starting the drug and then annually thereafter. This information provided by Neil I. Stahl, MD & Tongalp H. Tezel, MD was first printed in the The Moisture Seeker, SSF's patient newsletter for members. Minimum treatment guidelines recommend that every patient taking Hydroxychloroquine Plaquenil should have an annual eye exam after being on the medication for 5-years. But because your vision is priceless, Stonewire recommends annual eye health exams to all our patients on these medications and potentially we may escalate the frequency to every 6-months after 5-years. Of course the aim is avoid drug related retinal toxicity, which on ophthalmic examination, appears as the classic Bull’s eye change affecting the macula. Once retinal toxicity from hydroxychloroquine occurs, it is thought that the retinal changes are permanent and the disease can progress even if hydroxychloroquine is stopped for 1 to 3 years. Initially, central visual acuity may be unaffected, but the patient may notice related paracentral scotomas that often interfere with reading. The associated classic retinal toxicity is described as a bull’s eye maculopathy (ring of depigmented retinal pigment epithelium that spares the foveal area). Do you need a baseline eye exam before taking hydroxychloroquine Eye screening for patients taking hydroxychloroquine Plaquenil, Stonewire Optometry-Blog-Hydroxychloroquine Why you need an. Chloroquine phosphate pricePlaquenil premaculopathy It is recommended that you have an eye exam within the first year of use, then repeat every one to five years based on current guidelines. Tell Your Doctor Although there are few drug interactions with hydroxychloroquine, to be safe be sure to tell your doctor about all of the medications you are taking, including over-the-counter drugs and natural remedies. Hydroxychloroquine Plaquenil. My Take on New Ocular Screening Guidelines for Plaquenil.. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. May 24, 2019 If you are allergic to hydroxychloroquine; any part of hydroxychloroquine; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. If you have had any eye changes or changes in eyesight due to hydroxychloroquine or drugs like this one. If you have psoriasis. If you have porphyria. If you are taking cimetidine. If you are taking any drugs that can cause a certain type of heartbeat that is not normal prolonged QT interval. Plaquenil is the one drug that you need the eye exam prior to starting the drug as they really need that baseline. If it's going to affect your eyes, tends to do so in the first 6 months. but I don't think MTX is the same.doc hasn't made me get it prior to treatment but he is adamant about yearly eye exams. Plaquenil-induced toxicity usually will not occur before five years of taking the drug. “Eye damage due to Plaquenil is not common,” he says. “Rarely will anybody who has good vision and minimal symptoms develop loss of central vision or ability to read if annual screening is done and visual are symptoms reported as soon as they occur so the medication can be stopped if toxicity occurs.