Eye screening tests for plaquenil guidelines

Discussion in 'Without A Doctor Prescription' started by gordei4, 21-Feb-2020.

  1. rormzoomele Well-Known Member

    Eye screening tests for plaquenil guidelines


    She suffered from Sjogren syndrome and inflammatory arthritis and was currently treated with prednisone and methotrexate. She was previously treated with hydroxychloroquine (Plaquenil) 200mg bid (6.5mg/kg) for 10 years, which was stopped one year prior to presentation.

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    Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been replaced by HCQ. Most rheumatologists recommend patients undergo a baseline eye examination prior to starting Plaquenil and be re-examined in the future depending on their risk for developing the condition. Risk factors include advanced age and having pre-existing retinal disease. Previous 30 recommendations by the AAO to limit HCQ dosing to 6.5 mg/kg of ideal body weight have been 31 revised to 5 mg/kg of actual body weight 5. Some authors recommend 6.5 mg/kg of actual 32 body weight with a cap at 400 mg per day and further adjustments for renal insufficiency 10.

    Review of systems: Blurred vision, halos, dry eye, dry mouth, gastroesophageal reflux, joint pain Pupils: Reactive to light in each eye from 5 mm in the dark to 2 mm in the light. Extraocular movements: Full, both eyes (OU) Confrontation visual fields: Full OU Intra-ocular pressure The optic nerves appeared healthy with a 0.3 cup-to-disc ratio. Past Ocular History: None Medical History: Sjogren syndrome and inflammatory arthritis, supraventricular tachycardia, anxiety, depression, peptic ulcer disease Medications: prednisone, methotrexate, amitriptyline, ranitidine, estradiol, tizanidine, diltiazem, Restasis Allergies: codeine, droperidol Family History: heart disease, arthritis, cancer Social History: occasional alcohol but no tobacco or intravenous drug use.

    Eye screening tests for plaquenil guidelines

    PATIENT FACT SHEET Hydroxychloroquine Plaquenil, Plaquenil Side Effects on Your Eyes and Vision

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  6. Revised recommendations on screening for chloroquine and hydroxychloroquine retinopathy. Marmor MF1, Kellner U, Lai TY, Lyons JS, Mieler WF; American Academy of Ophthalmology. Author information 1Eye Institute at Stanford, Stanford University, Palo Alto, California, USA.

    • Revised recommendations on screening for chloroquine and..
    • AMERICAN COLLEGE OF RHEUMATOLOGY.
    • Protecting your eyesight when taking Plaquenil Lupus..

    Hydroxychloroquine And Chloroquine Screening 2016 AAO Recommendations The American Academy of Ophthalmology released an updated set of screening recommendations for hydroxychloroquine Plaquenil and chloroquine to account for the many studies that have shown the effects of these medications on the retina 1. The wider visual field tests, such as 24-2, are not sufficiently sensitive to screen the parafoveal region and may miss small scotomas. These tests are therefore not recommended as screening tools. Nevertheless, it is doubtful that the 10-2 visual field test is sufficiently effective as a screening tool. Safe use of Plaquenil. In our eye clinic we frequently see patients who need to be screened because they have been prescribed hydroxychloroquine Plaquenil and have concerns, so I wanted to write a short article summarizing the necessity and purpose of proper eye screening in these individuals.

     
  7. Stusa New Member

    Lower Back Pain Symptoms, Diagnosis, and Treatment Here are 4 common underlying causes of back stiffness with or without pain: Tightness in certain groups of muscles in your thighs and/or hips may alter the biomechanics of your spine. Thyroid Disease and Arthritis How They're Connected Joint Pain Johns Hopkins Sjögren’s Center Will you have Back pain with Plaquenil - eHealthMe
     
  8. KentavrOlimp Well-Known Member

    On the molecular mechanism of chloroquine's antimalarial. Chloroquine is thought to exert its antimalarial effect by preventing the polymerization of toxic heme released during proteolysis of hemoglobin in the Plasmodium digestive vacuole. The mechanism of this blockade has not been established. We incubated cultured parasites with subinhibitory doses of 3Hchloroquine and 3H quinidine. These 3Hquinoline compounds became associated with hemozoin.

    Aralen Chloroquine Uses, Dosage, Side Effects.