Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Mycophenolate and hydroxychloroquine Plaquenil cause fatigue Chloroquine resistance prophylaxis RECOMMENDED SCREENING. Baseline screening within 1 year of initiating medication. Annual screening after five years if no risk factors. Biomicroscopy, 10-2 HVF and SD-OCT on annual screening. Ancillary testing optional if no risk factors or other ocular comorbidities on baseline screening however commonly tested. Ocular manifestations of hydroxychloroquine include corneal verticillata and retinal toxicity. Verticillata are cornea deposits of salts within the corneal epithelium. This condition does not cause symptoms and is reversible with cessation of the medication. Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been replaced by HCQ. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Plaquenil screening ocular Hydroxychloroquine toxicity - EyeWiki, Hydroxychloroquine Plaquenil Toxicity and. Chloroquine falciparum target Plaquenil Hydrochloroquine or Aralen Chloroquine • Annual screening after 5 years of use **Interesting, The Royal College of Ophthalmologists in Great Britain does NOT recommend routine screening for toxicity with antimalarial drug use Early Plaquenil Toxicity Detected without Bull’s Eye Maculopathy. Recommendations on Screening for Chloroquine and.. My Take on New Ocular Screening Guidelines for Plaquenil.. Standards for current Plaquenil care. Most optometrists have easy access to OCT imaging, and may even have autofluorescence cameras. MultifocalERG is the least likely test that will be found at your local eye doctor's office, but some surgery centers or larger teaching hospitals may have an ERG on site. via Plaquenil, hydroxychloroquine HCQ, is an anti-malarial medication that has been proven to be useful in the treatment of patients with rheumatoid arthritis RA, systemic lupus erythematosus SLE and other inflammatory and autoimmune diseases. Ocular Surgery News The American Academy of Ophthalmology has published several dosing and screening recommendations for hydroxychloroquine to avoid potential retinal toxicity, yet some patients.