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Zithromax 500mg for 3 days CONCLUSIONS The results show that azithromycin is a safe and effective alternative in the treatment of inflammatory acne with few side-effects and good compliance, and suggest the need for further investigation with a clinical trial that will compare the long-term efficacy and tolerability. where can i purchase retin a Answer - Posted in acne treatment, acne, adapalene, azithromycin - Answer The azithromycin will not help/cure the scars that you already. Find a comprehensive guide to possible side effects including common and rare side effects when taking Zithromax Azithromycin for healthcare professionals. Shelley Moore is a journalist and award-winning short-story writer. She specializes in writing about personal development, health, careers and personal finance. Moore has been published in "Family Circle" magazine and the "Milwaukee Sentinel" newspaper, along with numerous other national and regional magazines, daily and weekly newspapers and corporate publications. View Full Profile Patients have several options for taking Zithromax for acne treatment. Packages of six are commonly called a Z-Pak, and include a first day's dose of 500 mg, and four 250 mg dosages for the next four days. Patients take one Z-Pak each month, or a treatment starting on the 1st and another on the 15th. Other approaches involve taking 200 mg or 500 mg of the medication three times a week for 8 to 10 weeks, or taking Zithromax three days on and seven days off for three cycles. Zithromax, like many other antibiotics, can lead to a severe condition called pseudomembranous colitis, resulting in severe diarrhea. Taking Zithromax may increase the risk of developing oral and vaginal yeast infections. 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